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What is ALS Disease?

What is Amyotrophic Lateral Sclerosis (ALS)?

ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that mainly affects the nerve cells located in the brain and spinal cord

The worth Amyotrophic is Greek in origin. “A” simply means no, “Myo” means muscle, whereas “trophic” means nourishment. Hence, amyotrophic simply means “no nourishment for the muscle” and when a muscle lacks nourishment is atrophies and withers away.

"Lateral" refers t the patients’ spinal cords where some of the nerve cells controlling the muscles are found. The more the are degenerates, the more it scars causing it to hardened, causing “sclerosis”.
Motor neuron cells from the brain reach down to the spinal cord and then from the spinal cord they reach all the muscles in the body. As soon as these motor neurons degenerate because of ALS, they will die. The brain will therefore be unable to control voluntarily the muscles in the body, affecting a person’s ability to speak, move, eat, swallow and breathe.
Upper motor neurons, lower motor neurons, found in the brain and motor neurons in spinal cord begin to die and are no longer able of sending messages to the voluntary muscles in the body. Lacking signals from the brain and spine, muscles are incapable of functioning, which leads to their weakening and their death. The body loses its ability to control voluntary movement of any kind.

How can Stem Cells Help with ALS?

Amyotrophic Lateral Sclerosis (ALS), is a progressive neurodegenerative condition affecting primarily nerve cells located in the spinal cord and brain. It involved the breakdown of motor neurons in the patients´ bodied.

It is common for those suffering from ALS to experience weakness in their limbs that will inevitably lead to a progressive paralysis, difficulty in breathing and, ultimately, death.

Clinical research has shown how Mesenchymal Stem Cells (MSC) therapy may represent a promising approach to treat ALS. MSC transplantations may delay the progression of the disease and help improve the symptoms of ALS.

Patients who undergo Stem Cell Therapy for their Amyotrophic Lateral Sclerosis can expect the following improvements:

• Improved breathing
• Improved walking and gait, fewer falls
• Improved chewing and swallowing
• Better cognition and behavioral changes
• Better ability to talk, less slurred speaking
• Less spasticity, more flexibility in the muscles, muscles are not as tight
• Fewer cramps or muscle twitches
As of today, there is no proper cure for ALS, and anyone diagnosed with ALS can expect to die within 3-5 years, mainly because of respiratory failure.

Fortunately, for those reading these lines, Stem Cells do indeed offer a promising chance to treat neurodegenerative disorders, including ALS. Mesenchymal stem cells (MSCs) have proven to be very beneficial for many patients who suffer from neurodegenerative diseases.

The main reason why mesenchymal stem cells are efficient in helping patients suffering from ALS, is predominantly because of the paracrine effect that is caused by the release of growth factors, free nucleic acids, lipids, cytokines plus extra-cellular vesicles, all of which are secreted biomolecules that bring about tissue repair, modulate the body’s immune system, help as anti-inflammatories and cause antiapoptotic activities.

According to countless studies, Mesenchymal Stem Cells from the Umbilical Cord can differentiate into several neuro-regulatory molecules, which can lead to an increase of several factors such as brain-derived neurotropic factor, glial cell-derived neurotropic factor, vascular endothelial growth factor, insulin-like growth factor and Glucagon-like pepetide-1.

On top of that, neural stem cells transplanted on the spot where the nerve injury is located can promote functional recovery as they produce trophic factors that can cause the regeneration of host neurons. If administered intravenously, mesenchymal stem cells can cross the blood-brain barrier and migrate seamlessly to where the neural injury is found.

What is the Stem Cell Treatment for ALS?

For patients suffering from ALS, the ideal stem cells according to many experts are Mesenchymal Stem Cells extracted from the Umbilical Cord.

With the help of our partner clinic in San José, Costa Rica, our ALS patients will receive a 4-day treatment plan that will include the following:

• 120 million Mesenchymal Stem Cells per day, which have been previously culture and expanded from the umbilical cord tissue.

In total, the patient will receive 480-500 Mesenchymal Stem Cells.

• Platelet-rich plasma therapy

• An Antioxidant Therapy with Vitamin C and Glutathione
• Ozone Therapy

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All medical treatments have varied outcomes. Therefore, results from the procedures will vary from patient to patient. This website is for educational purposes only. It is not meant to be a substitute for the diagnosis, treatment and advice of your trusted MD. Luxus Stem Cells educates and facilitates access to medical treatments and services. The ultimate responsibility for the treatment is with the treatment providers, clinics and hospitals.